Multi-layered porous hollow fiber membrane for use in cell cultu

Details Multi-layered porous hollow fiber membrane for use in cell cultu Multi-layered porous hollow fiber membrane for use in cell cultu

1990-08-01

1992-09-22

Robinson, Douglas W.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

435313, 435285, 4352401, 21050021, 21050022, 21050029, 21050030, C12N 500, B01D 3900, C12M 104

Patent

active

051496496

ABSTRACT:
A method for culturing cells by supplying oxygen to a culture medium through a multilayer composite membrane consisting of a porous layer(s) and a nonporous layer(s) having a thickness of less than 10 micrometers laminated one after the other. By using this multilayer composite membrane for supplying oxygen to the culture medium, oxygen can be supplied to the culture medium and/or the culture broth without causing foaming in the culture medium, cell growth inhibition or reduction in productivity of cellular products.

REFERENCES:
patent: 4826599 (1989-05-01), Bikson
patent: 4853128 (1989-08-01), Wrasidlo
patent: 4870018 (1989-10-01), Lehmann

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