Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills
Patent
1998-05-29
1999-12-21
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Tablets, lozenges, or pills
424468, 424472, 424474, 424476, 424475, 424479, 424482, A61K 922, A61K 924
Patent
active
060045825
ABSTRACT:
The present invention provides a simple and improved multi-layered osmotic device (1) that is capable of delivering a first active agent in an outer lamina (2) to one environment of use and a second active agent in the core (5) to another environment of use. Particular embodiments of the invention provide osmotic devices in which the first and second active agents are similar or dissimilar. An erodible polymer coat (3) between an internal semipermeable membrane (4) and a second active agent-containing external coat (2) comprises poly(vinylpyrrolidone)-(vinyl acetate) copolymer. This particular erodible polymer results in an improved multi-layered osmotic device possessing advantages over related devices known in the art. The active agent in the core (5) is delivered through a pore (6) containing an erodible plug (7). The osmotic device (1) can be coated by a final finish coat (8).
REFERENCES:
patent: 4014334 (1977-03-01), Theeuwes et al.
patent: 4335099 (1982-06-01), Funakoshi et al.
patent: 4576604 (1986-03-01), Guittard et al.
patent: 4673405 (1987-06-01), Guittard et al.
patent: 4801461 (1989-01-01), Hamel et al.
patent: 4810502 (1989-03-01), Ayer et al.
patent: 5035897 (1991-07-01), Ayer et al.
patent: 5558879 (1996-09-01), Chen et al.
patent: 5681584 (1997-10-01), Savastano et al.
Faour Joaquina
Mayorga Jorge
Channavajjala Lakshmi
Laboratorios Phoenix U.S.A, Inc.
Matos Rick
Page Thurman K.
LandOfFree
Multi-layered osmotic device does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Multi-layered osmotic device, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Multi-layered osmotic device will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-502403