Multi-label complex for enhanced sensitivity in electrochemilumi

Details Multi-label complex for enhanced sensitivity in electrochemilumi Multi-label complex for enhanced sensitivity in electrochemilumi

1995-05-09

1997-10-21

Jones, W. Gary

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 5, 435 912, 435 71, 435 79, 536 266, 536 243, 536 2432, 536 2433, 252515, C12Q 168, C12Q 170, C12P 1934, C07H 2104

Patent

active

056795190

ABSTRACT:
A nucleotide probe complex which enhances the ability to discriminate low level samples in electrochemiluminescent assays. The complex is composed of a platform molecule to which multiple copies of an organometallic electrochemiluminescent label and an oligonucleotide probe are separately attached. Preferably the complex is capped with streptavidin. Use of the complex permits detection of 1000 copies of analyte per sample in less than one hour.

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