Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage
Patent
1989-02-06
1995-09-05
Spiegel, Carol A.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving virus or bacteriophage
435 7920, 435 7930, 435 7940, 435 7950, 435962, 435973, 435974, 436518, 436523, 436524, 436528, 436531, 436825, C12Q 170
Patent
active
054478375
ABSTRACT:
The present invention provides a test strip for detecting, in a sample from a human subject, the presence of an antigenic substance which comprises a solid support, an antibody directed against the antigenic substance bound to a first discrete area on the solid support, an anti-human antibody bound to a second discrete area on the solid support as a positive control, and an antibody directed against an antigen which does not naturally occur in human subjects bound to a third discrete area on the solid support as a negative control. The present invention also provides a test strip for detecting, in a sample from a human subject, the presence of an antibody which comprises a solid support, an antigenic substance bound to a first discrete area on the solid support, an anti-human antibody bound to a second discrete area on the solid support as a positive control, and a negative control bound to a third discrete area on the solid support. The invention further provides a test strip for detecting the presence of an antibody and antigenic substance, which may additionally comprise an antibody-based reagent directed against the antigenic substance in an immune complex and native human antibody thereto. The invention also provides a method for detecting in a sample from a human subject the presence of an antigenic substance or antibody or both using the aforementioned test strips.
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Clinical Chemistry, 3
Calypte, Inc.
Spiegel Carol A.
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