Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2005-11-22
2005-11-22
Kemmerer, Elizabeth (Department: 1646)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C435S069400, C435S069500, C435S455000, C435S325000, C435S252300, C435S320100, C530S350000, C530S351000, C536S023400, C536S023500, C536S023510
Reexamination Certificate
active
06967092
ABSTRACT:
Disclosed are novel multi-functional chimeric hematopoietic receptor agonist proteins, DNAs which encode the multi-functional chimeric hematopoietic receptor agonist proteins, methods of making the multi-functional chimeric hematopoietic receptor agonist proetiens and methods of using the multi-functional chimeric hematopoietic receptor agonist proteins.
REFERENCES:
patent: 4703008 (1987-10-01), Lin
patent: 5376367 (1994-12-01), Williams
patent: 5420247 (1995-05-01), Gearing et al.
patent: 5554512 (1996-09-01), Lyman et al.
patent: 5635599 (1997-06-01), Pastan et al.
patent: 423 980 (1991-04-01), None
patent: 0 627 487 (1994-05-01), None
patent: 676 470 (1995-10-01), None
patent: WO 91/05795 (1991-05-01), None
patent: WO 92/04455 (1992-03-01), None
patent: WO92/06116 (1992-04-01), None
patent: WO 94/24160 (1994-10-01), None
patent: WO 94/25055 (1994-11-01), None
patent: WO94/26891 (1994-11-01), None
patent: WO94/28391 (1994-12-01), None
patent: WO95/21197 (1995-08-01), None
patent: WO 95/21254 (1995-08-01), None
patent: WO95/27732 (1995-10-01), None
patent: WO 96/14410 (1996-05-01), None
patent: WO 97/12985 (1997-04-01), None
patent: WO 97/38101 (1997-10-01), None
Chaudhary et al., Nature 339:394-397, Jun. 1989.
Bowie et al., Science 247:1306-1310, 1990.
Reeke et al, “Three-Dimensional Structure of Favin: Saccharide Binding-Cyclic Permutation in Leguminous Lectins”, Science, Nov. 28, 1986, vol. 234 pp 1108-1111.
Luger et al, “An 8-fold Ba Barrel Protein with Redundant Folding Possibilities”, Protein Engineering, vol. 3 pp 249-258.
Cunningham et al, “Favion versus concanavalin A: Circularly permuted amino acid sequences”, Proc. Natl. Acad. Sci. USA, Jul. 1979, vol. 76, No. 7, pp. 3218-3222.
Protasova et al, Circularly permuted dihydrofolate reductase ofE. colihas functional activity and a destabilized tertiary structure:, Protein Engineering, 1994, vol. 7, No. 11, pp. 1373-1777.
Zhang et al, “Circular Permutation of T4 Lysozyme”, Biochemistry, vol. 32, No. 46, 1993.
Luger et al, “Correct Folding of Circularly Permuted Variants of a Ba Barrel Enzyme in Vivo”, Science, vol. 243.
Hahn et al, “Native-like in vivo folding of a circularly permuted jellyroll protein shown by crystal structure analysis”, Proc. Natl. Acad. Sci. USA, 1994, vol. 91, pp. 10417-10421.
Lin et al, “Rearranging the domains of pepsinogen”, Protein Science, 1995, vol. 4, pp 159-166.
Yang et al, “Aspartate transcarbamoylase containing circularly permuted catalytic polypeptide chains”, Proc. Natl. Acad. Sci. USA, 1993, vol. 90, pp. 11980-11984.
Vignai et al, “Circular permutation within the coenzyme binding domain of the tetrameric glyceraldehyde-3-phosphate dehydrogenase fromBacillus stearothermophilus”, Protein Science, 1995, vol. 4., pp. 994-1000.
Goldenberg et al, “Circular and Circularly Permuted Forms of Bovine Pancreatic Trypsin Inhibitor”, J. Mol. Biol. 1983, vol. 165, pp. 407-413.
Hemperly et al, “Circular permutation of amino acid sequences among legume lectins”, TIBS, 1983, pp. 100-102.
Kreitman et al, “Circularly permuted interleukin 4 retains proliferative and binding activity”, Cytokine, 1995, vol. 7, No. 4, pp. 311-318.
Li et al, “Degradation of Ornithine Decarboxylase”, Mol. and Cel. Biol. 1993, vol. 13, No. 4, pp. 2377-2383.
Ritco et al, “Is the Continuity of the Domains Required for the Correct Folding of a Two-Domain Protein?”, Biochemistry, 1995, vol. 34, pp. 16543-16551.
Garrett et al, “Are turns required for the folding of ribonuclease T1?”, Protein Science, 1996, vol. 5., pp. 204-211.
Komar et al, “Kinetics of translation” FEBS Letters, 1995 vol. 376, pp. 195-198.
MacGregor et al, “A circularly permuted a-amylase-type”, FEBS Letters, 1996, vol. 378, pp. 263-266.
Koebnik et al, “Membrane Assembly of Circulary Permuted Variants”, JMB, 1995, vol. 250, pp. 617-626.
Buchwalder et al, “A fully active variant of Dihydrofolate Reductase with a circularly permuted sequence”, Biochemistry, 1992, vol. 31, pp. 1621-1630.
Viguera et al, “The order of secondary structure elements”, J. Mol. Biol., 1995, vol. 247, pp. 670-681.
Mullins et al. “Transposition of Protein Sequences: Circular Permutation of Ribonuclease T1”, J. Am. Chem. Soc., 1994, vol. 116, pp. 5529-5533.
Horlick et al, “Permuteins of interleukin 1B—a simplified approach for the construction of permutated proteins having new termini”, Protein Engineering, USA, 1992, vol. 5, pp. 427-431.
Kreitman et al, “A circularly permuted recombinant interleukin 4 toxin with increase activity”, Proc. Natl. Acad. Sci. USA, 1993, vol. 91, pp. 6889-3893.
Hannum et al, “Ligand for FLT3/FLK2 receptor tyrosine kinase regulates growth of hematopoietic stem cells and is encoded by variant RNAs”, Nature, 1994, vol. 368, pp. 643-664.
Lyman et al, “Cloning of the Human Homologue of the Murine flt3 Ligand: A Growth Factor for Early Hematopoietic Progenitor Cells”, The Am. Soc. of Hematology, USA, 1994, pp. 2795-2801.
Martin et al, “Primary Stucture and Functional Expression of Rat and human Stem Cell Factor DNAs” Cell, 1990, Vol. 63, pp. 203-211.
Feng Yiqing
Mc Kearn John P.
McWherter Charles A.
Minnerly John C.
Minster Nancy I.
Kemmerer Elizabeth
Winstead Sechrest & Minick PC
LandOfFree
Multi-functional chimeric hematopoietic receptor agonists does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Multi-functional chimeric hematopoietic receptor agonists, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Multi-functional chimeric hematopoietic receptor agonists will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3503902