X-ray or gamma ray systems or devices – Electronic circuit – With display or signaling
Reexamination Certificate
2000-10-10
2001-06-12
Kim, Robert H. (Department: 2882)
X-ray or gamma ray systems or devices
Electronic circuit
With display or signaling
C378S098110
Reexamination Certificate
active
06246747
ABSTRACT:
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT
BACKGROUND OF THE INVENTION
This invention relates generally to multi-energy x-ray machines and in particular to an improved method of discriminating between x-ray energies in such machines that permit lower x-ray flux rates and longer x-ray tube life.
Measuring the x-ray attenuation of an object at two different x-ray energies can reveal the composition of that object as a proportion of two arbitrarily selected basis materials. In the medical area, the basis materials may be “bone” and “soft tissue” allowing x-ray images to yield quantitative information about in vivo bone density for the diagnosis of osteoporosis. Alternatively, the basis “fat” and “lean” tissue may be selected to provide the indication of total body fat useful in the treatment of obesity or conversely wasting diseases.
Basis materials of “explosive” and “nonexplosive” materials may be used in the baggage scanning industry to augment images of the contents of baggage with the indication of the composition of the imaged contents.
Other basis materials may be selected for other industrial applications.
Referring to 
FIG. 1
, a commercially available multi-energy x-ray machine 
10
, in this case a bone densitometer, includes an x-ray source 
12
 supported at one end of a C-arm 
14
 positioned beneath a patient support table 
16
. An energy sensitive detector 
18
 is held by the other end of the C-arm 
14
 opposite the x-ray source receives a fan beam 
20
 of x-rays from the x-ray source 
12
. The fan beam is formed by a collimator (not shown) being one or more x-ray opaque shutters which block x-rays in all but narrow rectangular cross section as is well understood in the art.
A patient (not shown) positioned on the patient support table 
16
 may be scanned by motion of the C-arm with respect to the patient so that the x-ray fan beam 
20
 illuminates the patient over a region of interest.
Referring now to 
FIG. 2
, the x-ray source 
12
 may be a conventional polychromatic x-ray tube producing x-rays having a single mode spectrum 
22
 encompassing both high and low energy x-rays. The x-ray fan beam 
20
 is received by a k-edge filter 
24
 such as a cerium filter having an a real density of approximately 343 mg/cm
2
. The effect of the k-edge filter 
24
 is to preferentially block mid-energy x-rays to produce a bi-modal spectrum 
26
 having two peaks in regions of high and low energy.
The x-ray fan beam 
20
 continues through a patient 
28
 to arrive at an energy sensitive detector 
18
. Absorption of x-rays by the patient 
28
 produces at the energy sensitive detector 
18
 an attenuated bi-modal spectrum 
30
 also exhibiting the two peaks of bi-modal spectrum 
26
 but with lower amplitude.
The energy sensitive detector 
18
 may include a single scanned detector element or a number of detector elements 
32
 arranged in a linear or a real array. The detector elements in combination with motion of the C-arm (shown in 
FIG. 1
) allow a spatial mapping of x-ray signals to particular lines through the patient 
28
 and thus imaging of the patient 
28
 and spatially dependent measurements of the patient 
28
 such as area densities.
A detector is “energy sensitive” as used herein if it can distinguish the fluence of x-rays at different energies. A number of energy discriminating detector types are known in the art including scintillation-type detectors in which the x-rays are converted to light via a scintillator material. The amount of light for each event indicates the energy of the x-ray photon. The scintillation material may be followed by a photo multiplier tube to amplify the light output and the light may be measured by any of a number of light detectors including but not limited to Charge-Coupled Devices (CCD). Ionization detectors which work by measuring current formed by an ionized gas in the path of the x-rays can provide energy discrimination through measurement of the amount of current generated at each photon event. Solid state detectors using photodiodes can provide energy discrimination through the use of filters in a stacked or side-by-side configuration. Cadmium Zinc Telluride (CZT) provides direct electrical outputs in response to detected x-rays in the form of pulses for each incident photon where pulse amplitude or area is proportional to the photon's energy.
As shown in 
FIG. 2
, the output of the energy sensitive detector 
18
 for one detector element 
32
 may be a series of pulses 
34
 of varying times and heights corresponding to arrival times of related x-ray photons and the energies of those photons. The statistical distribution of the heights of the pulses 
34
 will conform generally to the attenuated bi-modal spectrum 
30
.
The signals for each detector element 
32
 may be received by an amplifier/pulse shaping circuit 
35
 and then by energy discriminator 
36
 (only one shown for clarity). The energy discriminator compares each pulse's height to a reference band 
38
 (implemented by a high and low voltage) which establish a high and low end point of an energy range for a plurality of window comparators 
40
(
a
) through 
40
(
c
). Generally, only pulses having heights within the corresponding reference band 
38
 will be passed by the window comparators 
40
 (i.e., pulse voltage peaks greater than the low voltage and lesser than the high voltage). Window comparators 
40
 can be constructed by two standard comparators, the first connected to the low references voltage and the pulse signal to provide a low output unless the pulse is above the low reference voltage and the second connected to the high references voltage and the pulse signal to provide a low output unless the pulse is below the high reference voltage. The outputs of the comparators are then logically ANDed together.
Referring now to 
FIGS. 2 and 4
, each reference band 
38
(
a
)-(
c
) generally establishes a different detection zone in the attenuated bi-modal spectrum 
30
. Reference band 
38
(
c
) in conjunction with window comparator 
40
(
c
) defines a low energy (LE) range causing the detection of only x-ray photons in the lower peak of attenuated bi-modal spectrum 
30
. Similarly, ranges 
38
(
a
) and 
38
(
b
) together, establish with their window comparators 
40
(
a
) and 
40
(
b
), a high-energy (HE) range detecting photons in the higher energy peak of attenuated bi-modal spectrum 
30
. Within the HE range, reference band 
38
(
b
) further establishes a lower range (LR) and reference band 
38
(
a
) establishes an upper range (UR) equally dividing the HE range. The purpose of these subranges will be described below.
Each window comparator 
40
(
a
) through 
40
(
c
) is followed by an integrator 
42
 such as a counter which counts the total number of pulses passed by the comparator within the respective ranges LE and HE and subranges LR and UR of range HE.
The output of the integrators 
42
 is provided to a basis material processor 
46
 acting on high and low energy attenuation information to establish the composition of the intervening material of the patient 
28
. The low energy attenuation information is provided directly by the output of the integrator associated with window comparator 
40
c 
of the LE range whereas the LR and UR images are added together to form the high energy attenuation information of the HE range. The latter addition is shown by summing block 
44
.
The basis material processor 
46
 operates according to well known techniques to process the high and low energy attenuation information to determine a basis material decomposition such as may be displayed to an operator on an interface terminal 
48
 of conventional design. The basis material processor 
46
 may be a microprocessor-based computer of a type well known in the art.
Referring now to 
FIG. 4
, variations in the signal chain between the detector elements 
32
 and the integrators 
42
 can cause the attenuated bi-modal spectrum 
30
 to vary in time by a compression or dilation along the horizontal or energy axis as indicated by attenuated bi-modal spectrum 
30
′. For
Lenz Daniel R.
Payne Randall K.
Washenko Robert A.
Wear James A.
GE Lunar Corporation
Ho Allen C.
Kim Robert H.
Quarles & Brady LLP
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