Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Reexamination Certificate
2005-06-27
2008-10-07
Carlson, Karen Cochrane (Department: 1656)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
Reexamination Certificate
active
07432360
ABSTRACT:
The present invention is directed to multi-dose erythropoietin formulations for parenteral administrations. The formulations contain one or more of the following preservatives benzethonium chloride, phenoxyethanol and phenylethyl alcohol.
REFERENCES:
patent: 3489837 (1970-01-01), Hyman
patent: 4377513 (1983-03-01), Sugimoto et al.
patent: 4703008 (1987-10-01), Lin
patent: 4806524 (1989-02-01), Kawaguchi et al.
patent: 4879272 (1989-11-01), Shimoda et al.
patent: 5045529 (1991-09-01), Chiang
patent: 5503827 (1996-04-01), Woog et al.
patent: 5554378 (1996-09-01), Uda et al.
patent: 5661125 (1997-08-01), Strickland et al.
patent: 0 199 992 (1986-11-01), None
patent: 0 459 795 (1991-05-01), None
Sandeep et al. Excipients and their use in injectable products (1997) PDA J. Pharm. Sci Technol. vol. 51, No. 4, pp. 166-171.
Durieux, Marcel E., M.D., “Synergistic Inhibition of Muscarinic Signaling by Ketamine Stereoisomers and the Preservative Benzethonium Chloride,”Anesthesiology86:1326-33 (1997).
Miyake, et al., “Purification of Human Erythropoietin,”J. Biol. Chem., 252(15):5558-64 (1977).
Sherwood, et al., “Erythropoietin Production by Human Renal Carcinoma Cells in Culture,”Endocrinology, 99(2):504-10 (1976).
Sherwood, et al., “Establishment of a Human Erythropoietin-Producing Renal Carcinoma Cell Line,”Clinical Research, 31:323A (1983).
Lee, Minhwa and Gu, Youngsoon, Ewha; New Pharmaceuticals; Women's University Publishing; p. 221 (1989).
Pivnick, H. et al.; “Preservatives for Poliomyelitis (Salk) Vaccine III 2-Phenoxyethanol,” J. Pharmaceutical Sciences; 53(8); 899-901 (1964).
Aventis Pharmaceuticals Inc.
Carlson Karen Cochrane
Vinson & Elkins LLP
LandOfFree
Multi-dose erythropoietin formulations does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Multi-dose erythropoietin formulations, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Multi-dose erythropoietin formulations will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4006760