Multi-component long-acting medicament formulation for implantat

Details Multi-component long-acting medicament formulation for implantat Multi-component long-acting medicament formulation for implantat

1988-02-03

1989-10-17

Swisher, Nancy A. B.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424430, 424487, A61K 922

Patent

active

048746126

ABSTRACT:
Multi-component implants which contain at least two shaped pieces containing active compound, wherein these shaped pieces contain biologically degradable copolymers of lactic acid and glycolic acid with a ratio by weight of lactide to glycolide of 90:10 to 60:40, and wherein there are at least two types of shaped pieces, A and B, type A containing copolymers with a content of lactide which is 5 to 15% by weight lower than in type B, release the active compound over a prolonged period, uniformly or with increasing amount released.

REFERENCES:
patent: 4293539 (1981-10-01), Ludwig et al.
CA103(2): 11404f, Sharon et al.

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