Multi-column separation devices and methods

Liquid purification or separation – With means to add treating material – Chromatography

Reexamination Certificate

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C210S656000, C422S070000, C422S105000

Reexamination Certificate

active

10638258

ABSTRACT:
Chromatographic separation devices include multiple batch-processed columns joined by a body structure and adapted to perform parallel analyses. Both slurry-packed and monolithic column embodiments are provided. One or more liquid-permeable frits of various types may be used to retain stationary phase material within columns. A fluidic distribution network may be used to distribute stationary phase material and/or mobile phase solvents to multiple columns. Separation devices, including microfluidic embodiments, may be fabricated with various materials including polymers. Multi-column fabrication and separation methods are provided.

REFERENCES:
patent: 3449938 (1969-06-01), Giddings
patent: 4175037 (1979-11-01), Benney et al.
patent: 4301139 (1981-11-01), Feingers et al.
patent: 4324689 (1982-04-01), Shah
patent: 4424127 (1984-01-01), Roeraade
patent: 4496461 (1985-01-01), Leeke et al.
patent: 4505539 (1985-03-01), Auracher et al.
patent: 4604198 (1986-08-01), Dailey et al.
patent: 4868129 (1989-09-01), Gibbons et al.
patent: 4891120 (1990-01-01), Sethi et al.
patent: 5135627 (1992-08-01), Soane
patent: 5160627 (1992-11-01), Cussler et al.
patent: 5190658 (1993-03-01), Vilenchik et al.
patent: 5194133 (1993-03-01), Clark et al.
patent: 5376252 (1994-12-01), Ekström et al.
patent: 5453153 (1995-09-01), Fan et al.
patent: 5478751 (1995-12-01), Oosta et al.
patent: 5658413 (1997-08-01), Kaltenbach et al.
patent: 5792943 (1998-08-01), Craig
patent: 5872010 (1999-02-01), Karger et al.
patent: 6004450 (1999-12-01), Northrup et al.
patent: 6054047 (2000-04-01), Hindsgaul et al.
patent: 6066848 (2000-05-01), Kassel et al.
patent: 6074725 (2000-06-01), Kennedy
patent: 6090278 (2000-07-01), Lally et al.
patent: 6095202 (2000-08-01), Colon et al.
patent: 6103199 (2000-08-01), Bjornson et al.
patent: 6129973 (2000-10-01), Martin et al.
patent: 6149815 (2000-11-01), Sauter
patent: 6171486 (2001-01-01), Green et al.
patent: 6197198 (2001-03-01), Messinger et al.
patent: 6210986 (2001-04-01), Arnold et al.
patent: 6221252 (2001-04-01), Hargro et al.
patent: 6224775 (2001-05-01), Foley et al.
patent: 6240790 (2001-06-01), Swedberg et al.
patent: 6245227 (2001-06-01), Moon et al.
patent: 6258263 (2001-07-01), Henderson et al.
patent: 6261430 (2001-07-01), Yager et al.
patent: 6263918 (2001-07-01), Lewis et al.
patent: 6264892 (2001-07-01), Kaltenbach et al.
patent: 6274726 (2001-08-01), Laugharn, Jr. et al.
patent: 6296771 (2001-10-01), Miroslav
patent: 6306590 (2001-10-01), Mehta et al.
patent: 6312888 (2001-11-01), Wong et al.
patent: 6387234 (2002-05-01), Yeung et al.
patent: 6432290 (2002-08-01), Harrison et al.
patent: 6436292 (2002-08-01), Petro
patent: 6444150 (2002-09-01), Arnold
patent: 6444461 (2002-09-01), Knapp et al.
patent: 6461515 (2002-10-01), Safir et al.
patent: 6464866 (2002-10-01), Moon et al.
patent: 6485069 (2002-11-01), Anderson
patent: 6494614 (2002-12-01), Bennett et al.
patent: 6497138 (2002-12-01), Abdel-Rahman et al.
patent: 6527890 (2003-03-01), Briscoe et al.
patent: 6537501 (2003-03-01), Holl et al.
patent: 6537506 (2003-03-01), Schwalbe et al.
patent: 6551839 (2003-04-01), Jovanovich et al.
patent: 6581441 (2003-06-01), Paul
patent: 6623860 (2003-09-01), Hu et al.
patent: 6627433 (2003-09-01), Frazier et al.
patent: 6635226 (2003-10-01), Tso et al.
patent: 6645377 (2003-11-01), Egorov et al.
patent: 6660149 (2003-12-01), Karger et al.
patent: 6663697 (2003-12-01), Kottenstette et al.
patent: 6664104 (2003-12-01), Pourahmadi et al.
patent: 6743356 (2004-06-01), Fermier et al.
patent: 6749749 (2004-06-01), Xie et al.
patent: 6812030 (2004-11-01), Ozbal et al.
patent: 6814859 (2004-11-01), Koehler et al.
patent: 6923907 (2005-08-01), Hobbs et al.
patent: 6986841 (2006-01-01), Zare et al.
patent: 2002/0017484 (2002-02-01), Dourdeville
patent: 2002/0048536 (2002-04-01), Bergh et al.
patent: 2002/0094533 (2002-07-01), Hess et al.
patent: 2002/0146840 (2002-10-01), Hage et al.
patent: 2002/0158022 (2002-10-01), Huang et al.
patent: 2002/0160139 (2002-10-01), Huang et al.
patent: 2002/0189947 (2002-12-01), Paul et al.
patent: 2002/0194909 (2002-12-01), Hasselbrink et al.
patent: 2002/0199094 (2002-12-01), Strand et al.
patent: 2003/0089663 (2003-05-01), Petro et al.
patent: 2003/0092056 (2003-05-01), Nagasawa
patent: 2003/0094415 (2003-05-01), Tanimura
patent: 2003/0118486 (2003-06-01), Zhou et al.
patent: 2003/0230524 (2003-12-01), Soga et al.
patent: 2004/0020834 (2004-02-01), Mincsovics et al.
patent: 2004/0084375 (2004-05-01), Hodgin et al.
patent: 2004/0134845 (2004-07-01), Paul et al.
patent: 1 106 244 (2001-06-01), None
patent: 1178309 (2002-02-01), None
patent: WO97/30347 (1997-08-01), None
patent: WO98/04909 (1998-02-01), None
patent: WO99/19717 (1999-04-01), None
patent: WO99/29497 (1999-06-01), None
patent: WO99/33559 (1999-07-01), None
patent: WO99/34909 (1999-07-01), None
patent: WO99/48599 (1999-09-01), None
patent: WO99/60397 (1999-11-01), None
patent: WO 00/21659 (2000-04-01), None
patent: WO 00/31528 (2000-06-01), None
patent: WO 00/51720 (2000-09-01), None
patent: WO 01/09598 (2001-02-01), None
patent: WO 01/38865 (2001-05-01), None
patent: WO 01/38865 (2001-05-01), None
patent: WO 01/50123 (2001-07-01), None
patent: WO 01/86283 (2001-11-01), None
patent: WO 02/22250 (2002-03-01), None
patent: WO 02/28509 (2002-04-01), None
patent: WO 02/28532 (2002-04-01), None
Chen, Xiaoxi et al.,A Prototype Two-Dimensional Capillary Electrophoresis System Fabricated in Poly(dimethylsiloxane), “Analytical Chemistry,” vol. 74, No. 8, Apr. 15, 2002, pp. 1772-1778.
Shediac, Renée et al.,Reversed-phase electrochromatography of amino acids and peptides using porous polymer monoliths, “Journal of Chromatography A,” 925 (2001) Elsevier Science B.V., pp. 251-263.
Gu{hacek over (c)}ek, Marjan et al.,Separation of Sugar Anomers by Capillary Electrochromatography, “Acta Chim. Slov.,” 2000, 47, 165-177.
Tennikova, Dr. Tataina et al.,Short high-throughput monolithic layers for bioaffinity processing, “LabPlus International,” Feb./Mar. 2002.
MacNair, John E. et al.,Ultrahigh-Pressure Reversed-Phase Liquid Chromatography in Packed Capillary Columns, “Analytical Chemistry,” vol. 69, No. 6, Mar. 15, 1997, pp. 983-989.
Khandurina, Julia et al.,Microfabricated Porous Membrane Structure for Sample Concentration and Electrophoretic Analysis, “Analytical Chemistry,” vol. 71, No. 9, May 1, 1999, pp. 1815-1819.
Poole, Colin F., “4.5 Column Preparation,”The essence of chromatography, 2003 Elsevier Science B.V., Amsterdam, the Netherlands, pp. 393-401.
Poole, Colin F., “5.6 Coupled-Column Systems,”The essence of chromatography, 2003 Elsevier Science B.V., Amsterdam, The Netherlands, pp. 451-455.
Poole, Colin F., “8.4.2 Column Technology,”The essence of chromatography, 2003 Elsevier Science B.V., Amsterdam, The Netherlands, pp. 664-668.
Krull, Ira S. et al., “2.3 Techniques for Packing Capillaries,”Capillary Electrochromatography and Pressurized Flow Capillary Electrochromatography, 2000 HNB Publishing, New York, NY, pp. 40-46.
Tan, Aimin et al.,Chip-Based Solid-Phase Extraction Pretreatment for Direct Electrospray Mass Spectrometry Analysis Using and Array of Monolithic Columns in a Polymeric Substrate, “Analytical Chemistry,” vol. 75, No. 20, Oct. 15, 2003, pp. 5504-5511.
“Multi-Parallel-HPLC,” Web document published at: http://www.sepiatec.com/download/phplc.pdf, SEPIAtec GmbH, Louis-Blériot-Strasse 5 D-12487 Berlin Germany.
Shediac, Renée, et al.,Reversed-phase electrochromatography of amino acids and peptides using porous polymer monoliths, “Journal of Chromatography A,” 925 (2001), pp. 251-263, Elsevier Science B.V.
MacNair, John E., et al.,Ultrahigh-Pressure Reversed-Phase Liquid Chromatography in Packed Capillary Columns, “Analytical Chemistry,” vol. 69, No. 6, Mar. 15, 1997, pp. 983-989.
MacNair, John E., et al.,Ultrahigh-Pressure Reversed-Phase Capillary Liquid Chromatogr

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