Chemistry: electrical and wave energy – Processes and products – Electrophoresis or electro-osmosis processes and electrolyte...
Reexamination Certificate
2006-09-26
2006-09-26
Noguerola, Alex (Department: 1753)
Chemistry: electrical and wave energy
Processes and products
Electrophoresis or electro-osmosis processes and electrolyte...
C204S603000
Reexamination Certificate
active
07112266
ABSTRACT:
Embodiments of a device and method are described which provide for control over the distortion of a sample zone upon exiting an electrophoresis separation channel. According to the teachings herein (i) the downstream regions of the channels, near the outlet ends, and/or (ii) the detection chamber, is/are configured so that distortion of one or more sample zones passing from the channels into and across the detection chamber can be controlled (e.g., reduced) in a fashion affording enhanced detectability. In certain embodiments, the lumens along the end regions of the separation channels progressively expand.
REFERENCES:
patent: 4592089 (1986-05-01), Hartman
patent: 4832815 (1989-05-01), Kambara et al.
patent: 5192412 (1993-03-01), Kambara et al.
patent: 5194133 (1993-03-01), Clark et al.
patent: 5268080 (1993-12-01), Kambara et al.
patent: 5277780 (1994-01-01), Kambara
patent: 5314602 (1994-05-01), Kambara et al.
patent: 5356776 (1994-10-01), Kambara et al.
patent: 5366608 (1994-11-01), Kambara
patent: 5374527 (1994-12-01), Grossman
patent: 5439578 (1995-08-01), Dovichi et al.
patent: 5529679 (1996-06-01), Takahashi et al.
patent: 5552028 (1996-09-01), Madabhushi et al.
patent: 5667656 (1997-09-01), Kambara
patent: 5741412 (1998-04-01), Dovichi et al.
patent: 5754524 (1998-05-01), Wark
patent: 5790727 (1998-08-01), Dhadwal et al.
patent: 5833826 (1998-11-01), Nordman
patent: 5858187 (1999-01-01), Ramsey et al.
patent: 5964998 (1999-10-01), Kambara
patent: 6017434 (2000-01-01), Simpson et al.
patent: 6045676 (2000-04-01), Mathies et al.
patent: 6156177 (2000-12-01), Takahashi et al.
patent: 6159353 (2000-12-01), West et al.
patent: 6174675 (2001-01-01), Chow et al.
patent: 6361671 (2002-03-01), Mathies et al.
patent: 6596140 (2003-07-01), Nordman et al.
patent: 0 882 982 (1998-12-01), None
patent: WO98/09161 (1998-03-01), None
patent: WO98/49549 (1998-11-01), None
patent: WO99/24828 (1999-05-01), None
patent: WO00/73780 (2000-12-01), None
Miura (“Review: Imaging and detection technologies for image analysis in electrophoresis,” Electrophoresis Apr. 2001, 22, 801-813).
Hanning et al. (“A liquid core wavelength fluorescence detector for multicapillary electrophoresis applied to DNA sequencing in a 91-capillary array,” Electrophoresis Sep. 2000, 21, 3290-3304)
Dolnik et al. “Capillary Electrophoresis on Microchip,” Electrophoresis, 2000, 21, 41-54.
Garcia Campana, et al., “Miniaturization of Capillary Electrophoresis Systems Using Micromachining Techniques,” J. Microcolumn Separations, 10 (4), 339-355, (1998).
Huang, et al., “End-Column Detection for Capillary Zone Electrophoresis,” Anal. Chem., 63 (2) 189-192, Jan. 15, 1991.
Krishnamoorthy, et al., “Analysis of Sample Injection and Band-Broadening in Capillary Electrophoresis Microchips,” Technical Proceedings of the MSM 2000, San Diego, CA, Mar. 27-29, 2000.
Grossman & Colburn, “Capillary Electrophoresis Theory & Practice,” Chapter 1 Academic Press (1992).
Sambrook, et al., eds. “Molecular Cloning: A Laboratory Manual” Second Edition, Chapter 5, Cold Spring Harbor Laboratory Press (1989).
Robson, et al., “Capillary Electrochromatography: A Review,” 357-372, 1997.
Swinney, et al., “Detection in capillary electrophoresis,” Electrophoresis, 2000, 21, 1239-1250.
Takahashi, et al., “Multiple Sheath-Flow Gel Capillary-Array Electrophoresis for Multicolor Fluorescent DNA Detection,” Anal. Chem., 1994, 66, 1021-1026.
Taylor, et al., “Axial-Beam Absorbance Detection for Capillary Electrophoresis,” Journal of Chromatography, 550 (1991) pp. 831-837.
Woolley, et al., “Capillary Electrophoresis Chips with Integrated Electrochemical Detection,” Anal. Chem. 70 (4), pp. 684-688, Feb. 15, 1998.
Woolley, et al., “Ultra-High-Speed DNA Fragment Separations Using Microfabricated Capillary Array Electrophoresis Chips,” Proc. Natl. Acad. Sci USA, vol. 91, pp. 11348-11352, Nov. 1994. Biophysics.
Xi et al., “Axial-Beam On-Column Absorption Detection for Open Tubular Capillary Liquid Chromatography,” Anal. Chem., vol. 62, No. 15, pp. 1580-1585, Aug. 1, 1990.
Nordmann Eric S
Reel Richard T
Applera Corporation
Noguerola Alex
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