Multi-bioreactor hollow fiber cell propagation system and method

Chemistry: molecular biology and microbiology – Condition responsive control process

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4352865, 4352875, 4352974, 435400, C12Q 300, C12M 300

Patent

active

056564210

ABSTRACT:
A unique hollow fiber multiple bioreactor system and method for the propagation of cells and the production of various cell propagation products is described. Simultaneous fluid flow through lumens of hollow fibers in bioreactors is maintained constant across multiple bioreactors so production is maintained essentially constant. The system and method include use of a flow block holder which allows a dissolved oxygen probe to be calibrated at the same pressure as the media in the bioreactor system.

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