Drug – bio-affecting and body treating compositions – Solid synthetic organic polymer as designated organic active... – Aftertreated polymer
Reexamination Certificate
2008-01-08
2008-01-08
Hartley, Michael G. (Department: 1618)
Drug, bio-affecting and body treating compositions
Solid synthetic organic polymer as designated organic active...
Aftertreated polymer
C424S078080, C424S078260, C424S078170, C424S078180
Reexamination Certificate
active
07316811
ABSTRACT:
The invention provides a multi-arm block copolymer for use in delivering a variety of bioactive agents. The copolymer of the invention contains a central core from which extend multiple (3 or more) copolymer arms. Each copolymer arm possesses an inner polypeptide segment and an outer hydrophilic polymer segment. Thus, the overall structure of the copolymer comprises an inner core region that includes the central core and the inner polypeptide segment, while the outer core region is hydrophilic in nature. The multi-arm copolymer of the invention is particularly useful for delivery of biologically active agents that can be entrapped within the inner core region.
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Emoto Kazunori
Ren Zhongxu
Zhao Xuan
Evans Susan T.
Hartley Michael G.
Nektar Therapeutics AL, Corporation
Rogers James W.
Wilson Mark A.
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