Radiant energy – Ionic separation or analysis – Ion beam pulsing means with detector synchronizing means
Reexamination Certificate
2006-12-05
2006-12-05
Wells, Nikita (Department: 2881)
Radiant energy
Ionic separation or analysis
Ion beam pulsing means with detector synchronizing means
C250S299000
Reexamination Certificate
active
07145134
ABSTRACT:
A detection scheme for time-of-flight mass spectrometers is described that extends the dynamic range of spectrometers that use counting techniques while avoiding the problems of crosstalk. It is well known that a multiple anode detector capable of detecting different fractions of the incoming particles may be used to increase the dynamic range of a TOFMS system. However, crosstalk between the anodes limits the amount by which the dynamic range may be increased. The present invention overcomes limitations imposed by crosstalk by using either a secondary amplification stage or by using different primary amplification stages.
REFERENCES:
patent: 2645734 (1953-07-01), Rajchman
patent: 4691160 (1987-09-01), Ino
patent: 4870265 (1989-09-01), Asmussen et al.
patent: 5061850 (1991-10-01), Kelly et al.
patent: 5166521 (1992-11-01), Hayashi et al.
patent: 5367162 (1994-11-01), Holland et al.
patent: 5644128 (1997-07-01), Wollnik
patent: 5689152 (1997-11-01), Boutot et al.
patent: 5777325 (1998-07-01), Weinberger et al.
patent: 6229142 (2001-05-01), Bateman et al.
patent: 6617768 (2003-09-01), Hansen
patent: 6674068 (2004-01-01), Kammei
patent: 6800847 (2004-10-01), Axelsson
patent: 6864479 (2005-03-01), Davis et al.
patent: 851549 (1981-07-01), None
patent: WO 99/38190 (1999-07-01), None
patent: WO 99/38191 (1999-07-01), None
patent: WO 99/38192 (1999-07-01), None
patent: WO 99/67801 (1999-12-01), None
patent: WO 01/18846 (2001-03-01), None
Barbacci, D. C., et al.—Multi-node Detection in Electrospray Ionization Time-of-Flight Mass Spectrometry; J Am Soc Mass Spectrom 1998, 9, 1328-1333; Elsevier Science, Inc., College Station, TX 77843, Brazos County, Texas.
Kristo, et al.—System for simultaneous count/current measurement with a dual-mode photon/particle detector; 1988 American Institute of Physics, Rev. Sci. Instrum. .59(3), Mar. 1988, pp. 438-442; Michigan State University, East Lansing, Michigan.
Fuhrer Katrin
Gonin Marc
McCully Michael I.
Raznikov Valeri
Schultz J. Albert
Fulbright & Jaworski L.L.P.
Ionwerks, Inc.
Quash Anthony
Wells Nikita
LandOfFree
Multi-anode detector with increased dynamic range for... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Multi-anode detector with increased dynamic range for..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Multi-anode detector with increased dynamic range for... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3672380