Radiant energy – Ionic separation or analysis – Methods
Reexamination Certificate
2005-06-21
2005-06-21
Lee, John R. (Department: 2881)
Radiant energy
Ionic separation or analysis
Methods
C250S287000
Reexamination Certificate
active
06909090
ABSTRACT:
A detection scheme for time-of-flight mass spectrometers is described that extends the dynamic range of spectrometers that use counting techniques while avoiding the problems of crosstalk. It is well known that a multiple anode detector capable of detecting different fractions of the incoming particles may be used to increase the dynamic range of a TOFMS system. However, crosstalk between the anodes limits the amount by which the dynamic range may be increased. The present invention overcomes limitations imposed by crosstalk by using either a secondary amplification stage or by using different primary amplification stages.
REFERENCES:
patent: 3760377 (1973-09-01), Attridge et al.
patent: 4691160 (1987-09-01), Ino
patent: 5644128 (1997-07-01), Wollnik et al.
patent: 5689152 (1997-11-01), Boutot et al.
patent: 6229142 (2001-05-01), Bateman et al.
patent: 2002/0175292 (2002-11-01), Whitehouse et al.
patent: 851549 (1981-07-01), None
patent: WO 99/38190 (1999-07-01), None
patent: WO 99/38191 (1999-07-01), None
patent: WO 99/38192 (1999-07-01), None
patent: WO 99/67801 (1999-12-01), None
patent: WO 01/18846 (2001-03-01), None
Barbacci, D. C., et al.—Multi-node Detection in Eloctrospray Ionization Time-of-Flight Mass Spectrometry; J Am Soc Mass Spectrom 1998, 9, 1328-1333; Elsevier Science, Inc., College Station, TX 77843, Brazos County, Texas.
Kristo, et al.—System for simultaneous count/current measurement with a dual-mode photon/particle detector; 1988 American Institute of Physics, Rev. Sci. Instrum. .59(3), Mar. 1988, pp. 438-442; Michigan State University, East Lansing, Michigan
Fuhrer Katrin
Gonin Marc
McCully Michael I.
Raznikov Valeri
Schultz J. Albert
Fulbright & Jaworski L.L.P.
Gill Erin-Michael
Ionwerks
Lee John R.
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