Multi-analyte assay device

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving cholesterol

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435 14, 435 15, 435 18, 435 19, 435 25, 435 28, 435288, 435289, 435291, 435808, 422 56, 422 58, 422100, C12Q 160, G01N 2111

Patent

active

051107244

ABSTRACT:
An assay device for assaying multiple analytes in a drop-size blood sample. The device includes a sample dispenser designed to distribute a small-volume blood sample to multiple transfer sites, by capillary flow of the blood sample through sieving and distributing matrices which separate blood cells from serum as the sample fluid migrates toward the transfer sites. A test plate in the device carries multiple absorbent test pads, each containing reagent components for use in detection of a selected analyte. The test plate is mounted on the dispenser for movement toward and away from a transfer position at which the exposed surface regions of the pads are in contact with associated sample-transfer sites, for simultaneous transfer of sample fluid from such sites to the pads in the support.

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