Mucolytic mercaptoacylamidobenzoic and benzenesulfonic acid comp

Details Mucolytic mercaptoacylamidobenzoic and benzenesulfonic acid comp Mucolytic mercaptoacylamidobenzoic and benzenesulfonic acid comp

1975-05-21

1977-01-25

Drezin, Norman A.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

A61K 31195

Patent

active

040052222

ABSTRACT:
A mucolytic process is disclosed which comprises contacting N-(2-hydroxyethyl)mercaptoacetamidobenzamides or mercaptoacylamidobenzoic acids, mercaptoacetylsulfanilic acids and alkanoylthio derivatives thereof with mucus. Illustrative of compounds useful in the mucolytic process of the present invention are 4-(2-mercaptoacetamido)benzoic acid and N-(2-mercaptoacetyl)sulfanilic acid.

REFERENCES:
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patent: 3091569 (1963-05-01), Sheffner
patent: 3663690 (1972-05-01), Eichel et al.
patent: 3770824 (1973-11-01), Phillips et al.
patent: 3809697 (1971-10-01), Martin et al.
A. L. Sheffenr, Ann. New York Acad. Sci., 106, 298-310, (1963).
N. S. Poonia et al., Indian. J. Appl. Chem., 27(1) 32-33 (1964).

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