Mucolytic mercaptoacylamidobenzamides and process of using same

Details Mucolytic mercaptoacylamidobenzamides and process of using same Mucolytic mercaptoacylamidobenzamides and process of using same

1976-10-18

1978-06-20

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

260558A, 260558S, A61K 31165, C07C10320

Patent

active

040962776

ABSTRACT:
A mucolytic process is disclosed which comprises contacting N-(2-hydroxyethyl)mercaptoacetamidobenzamides or mercaptoacylamidobenzoic acids, mercaptoacetylsulfanilic acids and alkanoylthio derivatives thereof with mucus. Illustrative of compounds useful in the mucolytic process of the present invention are 4-(2-mercaptoacetamido)-benzoic acid and N-(2-mercaptoacetyl)sulfanilic acid.

REFERENCES:
patent: 2448939 (1948-09-01), Weissberger et al.
patent: 2520293 (1950-08-01), Weiss
patent: 2607789 (1952-08-01), Weiss
patent: 3091569 (1963-05-01), Scheffner
patent: 3663690 (1972-05-01), Eichel
patent: 3770824 (1973-11-01), Phillips
patent: 3809697 (1971-10-01), Martin et al.
Scheffner, Ann. New York Acad. Sci. 106, 298-310 (1963).
W. S. Poonia et al., Indian J. Applied Chem., vol. 27(1) 32-33 (1964).

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