Mucin peptide with immunoenhancing properties

Drug – bio-affecting and body treating compositions – Nonspecific immunoeffector – per se ; or nonspecific...

Reexamination Certificate

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Details

C424S280100, C424S277100, C424S573000, C424S185100, C514S002600, C530S300000

Reexamination Certificate

active

10113800

ABSTRACT:
An isolated peptide or polypeptide containing the sequence VSIGLSFPMLP (SEQ ID NO:1), found in the secreted form of human MUC1, that enhances an immune response when administered to a mammal, compositions containing the peptide, host cells producing the peptide and methods of use. The peptide or polypeptide may be conjugated to a carrier protein and administered as part of a vaccine or immunogenic composition for prevention or treatment of a disease or disorder.

REFERENCES:
patent: 5861381 (1999-01-01), Chambon et al.
patent: WO 92/07000 (1992-04-01), None
Smorodinsky et al. Biochem. Biophys. Res. Commun. 228: 115-121, 1996.
Kumar et al. J. Immunol. 148: 1499-1505, 1992.
Bennett et al. Cancer Res. 43: 4183-4190, 1983.

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