Mucin directed lipsome

Plastic and nonmetallic article shaping or treating: processes – Encapsulating normally liquid material – Liquid encapsulation utilizing an emulsion or dispersion to...

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Details

4284022, 42840224, 424450, 6048901, A61J 500, B32B 516, A01N 2500

Patent

active

049216449

ABSTRACT:
Mucin coated Sepharose is used as a laboratory model to measure the affinity of a postulated lipid composition in liposome configuration for binding to mucin. The preferred lipid composition provides a first lipid moiety which projects a postive charged ion. A second lipid moiety enhances the positive charge by neutralizing all intermediate negative charges of the first lipid. The result is a liposome with strong postive charge areas which will bind to mucin.

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patent: 4614796 (1986-09-01), Kawamata et al.
patent: 4751219 (1988-06-01), Kempen
patent: 4762720 (1988-08-01), Jizomoto
patent: 4762915 (1988-08-01), Kung et al.
patent: 4765987 (1988-08-01), Bonte et al.

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