Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2008-12-22
2010-10-19
Bernhardt, Emily (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S253090, C514S254020, C514S254050, C514S326000, C544S362000, C544S363000, C544S364000, C544S366000, C544S369000, C546S210000
Reexamination Certificate
active
07816360
ABSTRACT:
The present invention is concerned with novel aryl piperidine or piperazine compounds substituted with certain 5-membered heterocycles having apoB secretion/MTP inhibiting activity and concomitant lipid lowering activity. The invention further relates to methods for preparing such compounds, pharmaceutical compositions comprising said compounds as well as the use of said compounds as a medicine for the treatment of hyperlipidemia, obesity and type II diabetes.The invention further relates to methods for preparing such compounds, pharmaceutical compositions comprising said compounds as well as the use of said compounds as a medicine for the treatment of atherosclerosis, pancreatitis, obesity, hypertriglyceridemia, hypercholesterolemia, hyperlipidemia, diabetes and type II diabetes.
REFERENCES:
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patent: WO 01/96327 (2001-12-01), None
patent: WO 02/20501 (2002-03-01), None
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Backx Leo Jacobus Jozef
Jaroskova Libuse
Linders Joannes Theodorus Maria
Meerpoel Lieven
Roevens Peter Walter Maria
Bernhardt Emily
Janssen Pharmaceutica NV
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