MTbx protein and nucleic acid molecules and uses therefor

Details MTbx protein and nucleic acid molecules and uses therefor MTbx protein and nucleic acid molecules and uses therefor

1998-11-10

2000-02-29

Carlson, Karen Cochrane

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

530300, C07K 1400

Patent

active

060310782

ABSTRACT:
Novel MTbx polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length MTbx proteins, the invention further provides isolated MTbx fusion proteins, antigenic peptides and anti-MTbx antibodies. The invention also provides MTbx nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which a MTbx gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.

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