Surgery – Diagnostic testing – Detecting nuclear – electromagnetic – or ultrasonic radiation
Reexamination Certificate
2006-03-14
2009-08-18
Winakur, Eric F (Department: 3768)
Surgery
Diagnostic testing
Detecting nuclear, electromagnetic, or ultrasonic radiation
C128S922000
Reexamination Certificate
active
07577472
ABSTRACT:
Time course MRI data is acquired from the hippocampal region of the brain and processed to produce two indices that are a measure of the functional connectivity between locations therein. The MRI data is acquired while the brain is substantially at rest and the spontaneous low frequency component of the time course data at each location in the hippocampus is extracted and compared in a cross-correlation process. Also acquired is fMRI data which indicates those locations in the brain that should be included in the index calculations.
REFERENCES:
patent: 5603322 (1997-02-01), Jesmanowicz et al.
patent: 6490472 (2002-12-01), Li et al.
patent: 2002/0103428 (2002-08-01), deCharms
patent: 2002/0103429 (2002-08-01), deCharms
patent: 2005/0053550 (2005-03-01), Paskavitz et al.
patent: 2005/0197560 (2005-09-01), Rao et al.
Neuroradiology, Oct. 2002, vol. 225. No. 1 p. 253-259.
Francisco Varela, et al; The Brainweb: Phase Synchronization and Large-Scale Integration; Nature Reviews—Neuroscience; vol. 2, Apr. 2001; pp. 229-239.
Gyorgy Buzsaki et al; Neuronal Oscillations In Cortical Networks; Science, vol. 204, No. 5679; pp. 1927-1929; Jun. 25, 2004.
Mark J Lowe et al; Multiple Sclerosis: Low-Frequency Temporal Blood Oxygen Level-Dependent Fluctuations Indicate Reduced Functional Connectivity-Initial Results; Radiology, vol. 224, No. 1; 07-2002; pp. 184-192.
Shi-Jiang Li et al; Alzheimer Disease: Evaluation of A Functional MR Imaging Index As a Marker; Radiology; vol. 225, No. 1; pp. 254-259.
Leaon Glass; Synchronization and Rhythmic Processes in Physiology; Nature, vol. 410, Mar. 8, 2001; pp. 277-284.
Michael D. Greicius et al; Default-Mode Network Activity Distinguishes Alzheimer's disease from Health Aging: Evidence from Functional MRI ; PNAS; Mar. 30, 2004, vol. 101, No. 13; pp. 4637-4642.
Michael D. Greicius et al; Functional Connectivity in the Resting Brain: A Network Analysis of the Default Mode Hypothesis; PNAS; Jan. 7, 2003, vol. 10, No. 1; pp. 253-258.
Marcus E. Raichle et al; A Default Mode of Brain Function; PNAS; Jan. 16, 2001; vol. 98, No. 2, pp. 676-682.
Li Shi-Jiang
Wu Gaohong
Xu Guofan
Xu Yin
Quarles & Brady LLP
Rozanski Michael T
The MCW Research Foundation Inc.
Winakur Eric F
LandOfFree
MRI method for producing an index indicative of brain disorders does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with MRI method for producing an index indicative of brain disorders, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and MRI method for producing an index indicative of brain disorders will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4061411