Surgery – Diagnostic testing – Detecting nuclear – electromagnetic – or ultrasonic radiation
Reexamination Certificate
2003-05-12
2009-12-01
Casler, Brian (Department: 3737)
Surgery
Diagnostic testing
Detecting nuclear, electromagnetic, or ultrasonic radiation
C600S407000, C600S410000, C324S306000, C324S307000, C324S309000
Reexamination Certificate
active
07627360
ABSTRACT:
An MRI apparatus is provided to quantify perfusion (microcirculatory blood flow in the tissue) in a region to be imaged in a subject based an ASL (arterial spin labeling) technique. The apparatus comprises imaging, storing, and flow quantifying units. The imaging unit performs a scan according to the ASL technique on the region so that image data is acquired from the region. The storing unit stores relationship information between a concentration of tracer (water) and a flow of the perfusion. The relationship is obtained on a two-compartment model that uses two compartments placed inside and outside of a flow of blood that diffuses into the tissue of the region and that considers temporal changes in the diffusion of the microcirculatory blood flow into the tissue. The flow quantifying unit quantifies the flow of the perfusion by applying an amount derived from the image data to the relationship information.
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Casler Brian
Kabushiki Kaisha Toshiba
Kish James
Nixon & Vanderhye PC
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