Drug – bio-affecting and body treating compositions – Dentifrices
Patent
1994-05-26
1995-11-28
Cintins, Marianne M.
Drug, bio-affecting and body treating compositions
Dentifrices
A61K 716
Patent
active
054705614
ABSTRACT:
The present invention relates to anti-plaque mouthwash compositions that contain a zinc salt and Triclosan as the anti-plaque system. According to the present invention effective, clear and stable mouthwash compositions with a zinc salt and Triclosan and a humectant system can be obtained with a water level of more than 60% by weight, if the compositions further comprise a surfactant system that comprises a mixture of a nonionic and an anionic surface-active agent.
It is essential that the nonionic surface-active agent should be of the type H-(O-CH.sub.2 CH.sub.2).sub.a -(O-CH(CH.sub.3)CH.sub.2).sub.b -(O-CH.sub.2 CH.sub.2).sub.a -OH and should be present in an amount of from 0.5-3% by weight of the composition.
The amount of the anionic surface-active agent in the compositions of the present invention should be such, that the weight ratio of the nonionic to the anionic surfaceactive agent ranges from 4-35, preferably from 5-20.
REFERENCES:
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patent: 4937066 (1990-06-01), Vlock
patent: 4976954 (1990-12-01), Kleber et al.
European Search Report in European Patent Application 92203788.2, 1993.
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Chemical Abstracts of 140180U, vol. 111, No. 16, Oct. 16, 1989.
Boylan, J. C. "Liquids" The Theory and Practice of Industrial Pharmacy, 2nd Ed. 1976, Lea & Febiger, Philadelphia, pp. 541-546.
Klugkist Jan
Saxton Charles A.
Chesebrough-Pond's USA Co. Division of Conopco, Inc.
Cintins Marianne M.
Jarvis William R. A.
Mitelman Rimma
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