Multicellular living organisms and unmodified parts thereof and – Nonhuman animal – Transgenic nonhuman animal
Reexamination Certificate
2003-03-04
2010-10-26
Falk, Anne-Marie (Department: 1632)
Multicellular living organisms and unmodified parts thereof and
Nonhuman animal
Transgenic nonhuman animal
C800S008000, C800S013000, C800S014000
Reexamination Certificate
active
07820876
ABSTRACT:
The invention concerns a non-human mammal carrying a mutation in the gene coding for the alpha6 subunit of the nicotinic acetylcholine receptor (nAChR), said mutation preventing expression of said nAChR alpha6 subunit in a functional form in the mammal.The invention also concerns synaptosome preparations obtained from said animals and cell cultures obtained by mutation of the alpha6 subunit as defined above.
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Bessis Alain
Champtiaux Nicolas
Changeux Jean-Pierre
Falk Anne-Marie
Finnegan Henderson Farabow Garrett & Dunner LLP
Institut Pasteur
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