Mouse model of myxomatous valvular disease

Details Mouse model of myxomatous valvular disease Mouse model of myxomatous valvular disease

2007-01-23

2007-01-23

Shukla, Ram R. (Department: 1632)

Multicellular living organisms and unmodified parts thereof and

Nonhuman animal

Transgenic nonhuman animal

C800S008000, C800S009000, C800S022000

Reexamination Certificate

active

10365140

ABSTRACT:
An animal selected for lacking heparan sulfate 3-O-sulfotransferase-1 activity is provided. This animal exhibits characteristics associated with myxomatous valvular disease and is useful for identifying agents which prevent, delay or treat myxomatous valvular disease. Methods of diagnosing myxomatous valvular disease are also provided.

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