Multicellular living organisms and unmodified parts thereof and – Nonhuman animal – Transgenic nonhuman animal
Reexamination Certificate
2006-10-24
2006-10-24
Nguyen, Dave Trong (Department: 1632)
Multicellular living organisms and unmodified parts thereof and
Nonhuman animal
Transgenic nonhuman animal
C800S003000
Reexamination Certificate
active
07126040
ABSTRACT:
A mouse model for mammalian aging is disclosed. In one embodiment, the invention comprises a mouse having a genomic mutation in the exonuclease domain II (ExoII) of a mitochondrial DNA polymerase gamma (PolG) gene, wherein the mutation leads to high levels of mutations in polymerase mtDNA.
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Kujoth Gregory C.
Prolla Tomas A.
Montanari David A.
Nguyen Dave Trong
Quarles & Brady LLP
Wisconsin Alumni Research Foundation
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