Mouse-human chimaeric immunoglobulin heavy chain specific for th

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

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530387, 530808, 530809, 530828, 4351723, 4351722, 935 15, C07K 1300, C07K 1504, A61K 39395

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049354965

ABSTRACT:
A mouse-human chimaeric immunoglobulin heavy chain comprising (a) the amino acid sequence of a mouse immunoglobulin heavy chain variable region and (b) the amino acid sequence of a human immunoglobulin heavy chain constant region and reacting specifically with human common acute lympohocytic leukemia antigen and a chimaeric DNA fragment which encodes the amino acid sequence of the above mouse-human chimaeric immunoglobulin heavy chain.

REFERENCES:
patent: 4645738 (1987-02-01), Knowles et al.
patent: 4731244 (1988-03-01), Talle et al.
Neuberger et al, Nature, 312, 604-618, Dec. 13, 1984.
Marx, Science, 229, 455-446, Aug. 2, 1985.
Sharon et al, Nature, 309, 364-377, May 24, 1984.
Morrison, Science, 229, 1202-1207, Sep. 20, 1985.
Morrison et al, PNAS, 81, G 851-855, Nov. 1984.
Takeda et al, Nature, 314, 452-454, Apr. 4, 1985.
Deng et al, Blood, 61(4), 759-769, Apr. 1983.
Bakri et al, Cancer 54(2), 284-292, Jul. 15, 1984.
Munro, Nature, 312, 597, Dec. 13, 1984.
Oi et al, PNAS, 80, 825-829, 1983.
Roitt et al. (EDs.), in "Immunology", Chapter 5, pp. 5.1 to 5.9, 1985 pub. date.
Gillies et al, Cell, 33, 717-728, 1983 (Jul.).
Ochi et al., PNAS, 80, 6351-6355, 1983.
Ueda et al., Proc. Natl. Acad. Sci. USA vol. 79, pp. 4386-4390 Jul. 1982.
Boulianne et al., Nature, vol. 312, pp. 643-646 (1984).
Neuberger et al., Nature, vol. 314, pp. 268-270 (1983).

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