Mosaic infectious bursal disease virus vaccines

Chemistry: molecular biology and microbiology – Virus or bacteriophage – except for viral vector or... – Recovery or purification

Reexamination Certificate

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C435S235100, C435S456000, C435S463000, C435S464000, C435S466000

Reexamination Certificate

active

10046671

ABSTRACT:
The invention relates to Infectious Bursal Disease Virus (“IBDV”) and vaccines therefor. Provided are infectious recombinant Infectious Bursal Disease Virus (“rIBDV”) essentially incapable of growing in a cell that is not derived from a bursa cell, or an infectious rIBDV having retained at least part of the very virulent characteristics of a very virulent Infectious Bursal Disease Virus (“vvIBDV”).

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Mundt E. “Tissue culture infectivity of different strains of infectious busal disease virus is determined by distinct amino acid in V2” J. Gen. Virology vol. 80(1999), pp. 2067-2076.
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Muller et al., Biosynthesis of Virus-Specific Proteins in Cells Infected with Infectious Bursal Disease Virus and Their Significance as Structural Elements for Infectious Virus and Incomplete Particles, Journal of Virology, Oct. 1982, pp. 384-392, vol. 44, No. 1.
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