Morphological mutants of filamentous fungi

Details Morphological mutants of filamentous fungi Morphological mutants of filamentous fungi

2007-04-03

2007-04-03

Tate, Christopher R. (Department: 1655)

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Fungi

C435S254100, C435S173100, C435S254110

Reexamination Certificate

active

10883346

ABSTRACT:
The present invention relates to methods of obtaining a mutant cell from a filamentous fungal parent cell, comprising: (a) obtaining mutant cells of the parent cell; (b) identifying the mutant cell which exhibits a more restricted colonial phenotype and/or a more extensive hyphal branching than the parent cell; and (c) identifying the mutant cell which has an improved property for production of a heterologous polypeptide than the parent cell, when the mutant and parent cells are cultured under the same conditions.

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