Morphological mutants of filamentous fungi

Details Morphological mutants of filamentous fungi Morphological mutants of filamentous fungi

1997-03-13

2000-05-23

Lankford, Jr., Leon B.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Fungi

435 691, 43525411, 4352543, 4352548, 4351731, C12N 114, C12N 115, C12N 1300, C12P 2106

Patent

active

060664932

ABSTRACT:
The present invention relates to methods of obtaining a mutant cell from a filamentous fungal parent cell, comprising: (a) obtaining mutant cells of the parent cell; (b) identifying the mutant cell which exhibits a more restricted colonial phenotype and/or a more extensive hyphal branching than the parent cell; and (c) identifying the mutant cell which has an improved property for production of a heterologous polypeptide than the parent cell, when the mutant and parent cells are cultured under the same conditions.

REFERENCES:
patent: 4228241 (1980-10-01), Hiraga et al.
patent: 4816405 (1989-03-01), Yelton et al.
patent: 5364770 (1994-11-01), Berka et al.
patent: 5503991 (1996-04-01), Gwynne et al.
patent: 5536661 (1996-07-01), Boel et al.
patent: 5578463 (1996-11-01), Berka et al.
patent: 5602004 (1997-02-01), Jensen et al.
Wiebe et al. Mycological Research, vol. 95, pp. 1284-1288, 1991.
Wosten et al., J. of General Microbiology, vol. 137, pp. 2017-2023, 1991.
Wiebe et al., J. of General Microbiology, vol. 139, pp. 2811-2817, 1993.
Springer et al., Genes & Development, vol. 3, pp. 559-571, 1989.
Rodrigues et al., Mycol. Res., vol. 95, No. 2, pp. 169-177, 1991.
Pomes et al., FEMS Microbiology Letters, vol. 48, pp. 255-259, 1987.
Withers et al., Mycol. Res., vol. 98, No. 1, pp. 95-100, 1994.
Goldman et al., Rev. Brasil. Genet., vol. 12, No. 4, pp. 719-728, 1989.
A. Clutterbuck, J. of General Microbiology, vol. 136, pp. 1731-1738, 1990.
Rosato et al., Rev. Brasil. Genet. X, vol. 3, pp. 425-433, 1987.
Moscoso et al., Appl. Microbiology Biotechnology, vol. 26, pp. 365-368, 1987.
Almeida et al., Trans. Br. Mycol. Soc., vol. 1, pp. 139-143, 1984.
Banerjee et al., Can. J. Microbiol. vol. 27, pp. 367-369, 1981.
Koide et al., J. Gen. Appl. Microbiol. vol. 25, pp. 161-168, 1979.
Simpson et al., J. of General Microbiology, vol. 110, pp. 1-12, 1979.
Basu et al., Folia Microbiol., vol. 19, pp. 199-202 (1974).
Hondel et al., Antonie van Leeuwenhoek, vol. 61, pp. 153-160 (1992).
Wiebe et al., Mycol. Res., vol. 96, No. 7, pp. 555-562 (1992).
Anthony P.J. Trinci, Mycol. Res., vol. 96, No. 1, pp. 1-13 (1992).

Affiliated with

Also associated with

Rating

Morphological mutants of filamentous fungi does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Morphological mutants of filamentous fungi, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Morphological mutants of filamentous fungi will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1836145