Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2003-03-27
2009-11-24
Anderson, Rebecca L (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S236200, C544S132000, C544S138000, C544S146000, C544S162000
Reexamination Certificate
active
07622464
ABSTRACT:
Compounds of formula (I):wherein:R1represents substituted or unsubstituted heteroaryl;Y represents —(CRnaRnb)n—;Rnaand Rnbare each independently hydrogen or C1-6alkyl;n is an integer from 0 to 5;R2represents unsubstituted or substituted aryl or unsubstituted or substituted heteroaryl;R3and R4each independently represent hydrogen or C1-6-alkyl;R7represents hydrogen or C1-6alkyl;R8represents hydrogen or C1-6alkyl;and salts and solvates thereof;are CCR3 antagonists and are thus indicated to be useful in therapy.
REFERENCES:
patent: 5389635 (1995-02-01), Olson
patent: 5919776 (1999-07-01), Hagmann et al.
patent: 6031097 (2000-02-01), He et al.
patent: 0306440 (1989-03-01), None
patent: 04208267 (1992-07-01), None
patent: WO 95/32196 (1995-11-01), None
patent: WO 96/02534 (1996-02-01), None
patent: WO 96/39386 (1996-12-01), None
patent: WO 97/47601 (1997-12-01), None
patent: WO 98/56771 (1998-12-01), None
patent: WO 99/06384 (1999-02-01), None
patent: WO 99/21848 (1999-05-01), None
patent: WO 00/18767 (2000-04-01), None
patent: WO 02/26722 (2002-04-01), None
patent: WO 02/26723 (2002-04-01), None
Byrn et al., Solid-State Chemistry of Drugs, Second Edition, 1999, pp. 233-247.
Dressman et al., “Solid phase synthesis of urea libraries using a diversifiable thiophenoxy carbonyl linker,”Tetrahedron Letters39(22):3631-3634 (May 1998).
Makabe et al., “Synthesis of some nucleoside analogs of substituted 1,2,3-triazole,”Bull. Chem. Soc. Jap.45(8):2577-2579 (1972).
Ancliff Rachael Ann
Cook Caroline Mary
Eldred Colin David
Gore Paul Martin
Harrison Lee Andrew
Anderson Rebecca L
Glaxo Group Limited
Rick James P.
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