Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1987-01-30
1988-06-28
Ramsuer, Robert W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514863, 514825, 544153, A61K 31535, C07D41312
Patent
active
047539356
ABSTRACT:
The compounds and pharmaceutical compositions of Formula A, wherein Z is hydrogen or --C(O)R, where R is lower alkyl or aryl, and the pharmaceutically acceptable salts thereof, are useful as immunosuppressive agents, anti-inflammatory agents, anti-tumor agents, anti-viral agents, and anti-psoriatic agents. ##STR1##
REFERENCES:
patent: 3868454 (1975-02-01), Johnson
"Antitumor Activity of Derivatives of Mycophenolic Acid", Suzuki, et al., J. Antibiotics, 29(3), 275-285, 1975.
"A Gastroprotective Anti-Inflammatory Agent: the .beta.-Morpholinoethyl Ester of Niflumic Acid (Morniflumate)", Schiantarelli, et al., Agents and Actions, 14(2), 1984.
Allison Anthony C.
Eugui Elsie M.
Gu Chee-Liang L.
Lee William A.
Nelson Peter H.
Lowin David A.
Moran Tom M.
Ramsuer Robert W.
Syntex (U.S.A.) Inc.
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