Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1999-05-12
2000-10-31
Ramsuer, Robert W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
544144, A61K 315377, A61P 3708, C07D41302
Patent
active
06140327&
ABSTRACT:
The compound, ((3-(2-amino-1,2-dioxoethyl)-2-ethyl-1-(phenylmethyl)-1H-indol-4-yl)oxy)ac etic acid morpholino-N-ethyl ester, is disclosed together with its use as a highly bioavailable indole compound for inhibiting sPLA.sub.2 mediated release of fatty acids for treatment of conditions such as septic shock.
REFERENCES:
patent: 5654326 (1997-08-01), Bach et al.
Lipsky, James J., The Lancet, vol. 348, pp. 1357-1359, Nov. 16, 1996.
Beight Douglas Wade
Buben John Andrew
Morin, Jr. John Michael
Sall Daniel Jon
Sawyer Jason Scott
Benjamin Roger S.
Eli Lilly and Company
Ramsuer Robert W.
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