Morpholino containing pyrido (3,4-d) pyridazines

Details Morpholino containing pyrido (3,4-d) pyridazines Morpholino containing pyrido (3,4-d) pyridazines

1975-12-23

1976-12-21

Jiles, Henry R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602475DP, 260250AC, 424250, 4242484, 42424857, C07D47104

Patent

active

039988228

ABSTRACT:
Pyrido (3,4-d) pyridazine derivatives are provided herein of the formula: ##STR1## wherein R.sub.1 is hydrogen or an alkyl group of 1 to 4 carbon atoms; R.sub.2 is a substituted or unsubstituted phenyl, naphthyl, furyl or pyridyl, the number of the substituents being one of two, the substituents being those selected from the group consisting of lower alkoxy groups of 1 to 3 carbon atoms, lower alkyl groups of 1 to 3 carbon atoms, halogens and nitros; R.sub.3 is hydrogen or a lower alkoxy group of 1 to 4 carbon atoms; and R.sub.4 is a substituted or unsubstituted morpholino, piperidino or pyrrolidino, the substituents being one or two, the substituents being those selected from the group consisting of methyl and ethyl groups, and at least one of the residue R.sub.2 and the residue R.sub.4 is substituted by one or two substituents, and a pharmaceutically acceptable salt thereof. The compounds of the present disclosure have effective and strong diuretic action and exhibit low toxicity characteristics.

REFERENCES:
patent: 3948908 (1976-04-01), Yurugi et al.
Yurugi et al., "Chem. Abstracts", vol. 79 (1973), No. 78830w.
Yurugi et al., "Chem. Abstracts", vol. 82 (1975), No. 4281h.
Oka et al., "Chem. Abstracts", vol. 81 (1974), No. 63651f.

Affiliated with

Also associated with

Rating

Morpholino containing pyrido (3,4-d) pyridazines does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Morpholino containing pyrido (3,4-d) pyridazines, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Morpholino containing pyrido (3,4-d) pyridazines will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1838408