Morpholino containing benzamides

Details Morpholino containing benzamides Morpholino containing benzamides

1978-10-20

1980-07-01

Jiles, Henry R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

544169, 42424854, C07D29506, C07D29514

Patent

active

042107547

ABSTRACT:
Benzamides of the formula ##STR1## wherein X is halogen, trifluoromethyl or C.sub.3-4 -alkyl and Y is hydrogen, halogen or nitro,
and N-oxides thereof, prepared inter alia from N-(2-aminoethyl)-morpholine and an acid of the formula ##STR2## wherein X and Y are as hereinbefore set forth, are described. The end products are useful in the treatment of depressive conditions, that is, are useful as antidepressants.

REFERENCES:
patent: 3502623 (1970-03-01), Jucker et al.
patent: 3787419 (1974-01-01), Bruce
Chabrier et al. "Chem. Abstracts" vol. 51 (1957) p. 1187.
Kotelko et al. "Chem. Abstracts" vol. 79 (1973) No. 105,217K.
Morimoto et al. "Chem. Abstracts" vol. 75 (1971) No. 1,979w (Abstract of Japanese Patent 45 32421).

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