Morpholine derivatives as norepinephrine reuptake inhibitors

Details Morpholine derivatives as norepinephrine reuptake inhibitors Morpholine derivatives as norepinephrine reuptake inhibitors

2008-09-09

2008-09-09

Anderson, Rebecca L (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C544S149000

Reexamination Certificate

active

10577841

ABSTRACT:
Compounds of the general formula (I) are inhibitors of the reuptake of norepinephrine. As such, they may be useful for the treatment of disorders of the central and/or peripheral nervous system.

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Morilak et al., Progress in Neuro-Psychopharmacology & Biology Psychiatry, 29(2005), pp. 1214-1224.
Kato, Shiro, et al., “1-(1-Substituted-4-piperidinylmethyl)piperidine derivatives as 5-TH4 receptor agonists, pharmaceutical compositions containing them, and their use,” XP002317575, Database CA 'Online! Chemical Abstracts Service, Columbus, Ohio, US, retrieved from STN Database accession No. 2004:819908 abstract.
King, Frank, et al., “The synthesis of 2-morpholinecarboxylic acid derivatives and their elaboration to 1-aza-4-oxabicyclo′3.3.1!nonan-6-one”,Tetrahedron Letters, 32(20):2281-4, 1991.

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