Morpholine compounds and methods of use

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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42424858, 424250, 424267, 424324, 26029376, 260558R, 260559R, 544174, 544176, 544391, A61K 31535, C07D29518

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active

041155700

ABSTRACT:
Compounds of the formula ##STR1## wherein A is alkylene, R.sub.1, R.sub.2, and R.sub.3 are hydrogen or lower alkoxy, and R.sub.4 is ##STR2## in which R.sub.5 and R.sub.6 are hydrogen or lower alkyl, with the proviso that at least one of R.sub.5 and R.sub.6 is lower alkyl, and >X is oxygen, ##STR3## or >N--R.sub.7 wherein R.sub.7 and R.sub.8 are hydrogen or lower alkyl, depress the activity of the central nervous system when administered to a living animal.

REFERENCES:
patent: 2851494 (1958-09-01), Ehrhart et al.
Chiron et al., I, Bull. Chim. Soc. Fr., pp. 575-583 (1970).
Chiron et al., II, Bull. Chim. Soc. Fr., pp. 2145-2153 (1971).
Wawzonek et al., J. Org. Chem., vol. 36, p. 2470 (1971).
Vereshchagin et al., J. Org. Chem. USSR, vol. 9, pp. 514-518 (1973).
Woodman et al., J. Org. Chem., vol. 38, pp. 4288-4295 (1973).
Ramachandran et al., Chem. Abst., vol. 77, item 19329 (1972).
Sucrow et al., Ber., vol. 105, pp. 1621-1633 (1972).
Isowa et al., Chem. Abst., vol. 70, item 114858 (1969).
Seefelder, Chem. Abst., vol. 56, col. 1326 (1962).
Padwa et al., J. Am. Chem. Soc., vol. 93, pp. 2928-2935 (1971).
Laurence et al., Chem. Abst., vol. 70, item 77089 (1969).
Bersch et al., Chem. Abst., vol. 52, col. 14628 (1958).
Cromwell et al., J. Am. Chem. Soc., vol. 80, pp. 4573-4577 (1958).
Lukes et al., Chem. Abst., vol. 53, col. 15075 (1959).
Garzia et al., "Riv. di Farm.", VI, 75-78 (1975).
Tammiso, "Riv. di Farm.", VI, 71-74 (1975).
Sandrini et al., "Riv. di Farm.", VI; 7-15, 17-22, 23-33, 351-355 (1975).

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