Morphine compounds for pharmaceutical compositions

Details Morphine compounds for pharmaceutical compositions Morphine compounds for pharmaceutical compositions

2007-02-15

2011-10-18

Skowronek, Karlheinz R (Department: 1613)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C548S369400, C548S371400

Reexamination Certificate

active

08039640

ABSTRACT:
The invention relates to new morphine compounds of the formula:where R1represents a C1-6alkyl radical and the radicals R2and R3are independently selected from the group consisting of hydrogen atoms, methyl groups and acetyl groups.

REFERENCES:
patent: WO 02/098427 (2002-12-01), None
Excerpt fromNatural Products, “Alkaloids” (1997), p. 166, referencing Goerlitzer, K et al., “Mannich-Bases if Morphine, Isomorphines, and Chloromorphides”, Sci. Pharm., vol. 64 (1/4): pp. 391-398 (1996).
International Search Report issued by the European Patent Office for PCT/EP2007/001316 (May 25, 2007).
Hernandez-Delgadillo, G. P. et al. 2002. “Metamizol Potentiates Morphine Nociception But Not Constipation After Chronic Treatment.”European Journal of Pharmacology. Zusammenfassung. vol. 441, pp. 177-183.

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