Moraxella catarrhalis protein, gene sequence and uses thereof

Details Moraxella catarrhalis protein, gene sequence and uses thereof Moraxella catarrhalis protein, gene sequence and uses thereof

2007-12-25

2007-12-25

Campell, Bruce R. (Department: 1645)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Amino acid sequence disclosed in whole or in part; or...

C424S184100, C424S234100, C424S251100, C530S300000, C530S350000, C536S023700, C435S069700

Reexamination Certificate

active

10369299

ABSTRACT:
The invention discloses theMoraxella catarrhalisouter membrane protein polypeptide and polypeptides derived therefrom (collectively “OMP21”), nucleotide sequences encoding said OMP21, and antibodies that specifically bind OMP21. Also disclosed are pharmaceutical compositions including prophylactic or therapeutic compositions, which may be immunogenic compositions including vaccines, comprising OMP21, antibodies thereto or nucleotides encoding same. The invention additionally discloses methods of inducing an immune response toM. catarrhalisand OMP21 in an animal, preferably a human, methods of treating and methods of diagnosingMoraxellainfections in an animal, preferably a human, and kits therefor.

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