Moraxella catarrhalis BASB034 polypeptides and used thereof

Details Moraxella catarrhalis BASB034 polypeptides and used thereof Moraxella catarrhalis BASB034 polypeptides and used thereof

2003-03-10

2008-10-07

Foley, Shanon A. (Department: 1645)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S023100, C536S024100, C536S024320, C530S300000, C530S350000, C435S069100, C435S069700, C424S184100, C424S190100, C424S234100, C424S251100

Reexamination Certificate

active

07432366

ABSTRACT:
Provided areMoraxella catarrhalisBASB034 polypeptides and immunogenic fragments of BASB034 polypeptides. Preferably, the immunogenic fragments have at least 15 amino acids that match an aligned contiguous segment of SEQ ID NOs:2, 4, 6 or 8. The immunogenic fragments, when administered to a subject in a suitable composition (which can include an adjuvant, or a suitable carrier coupled to the fragment) raise an immune response that recognizes a polypeptide having the sequence of SEQ ID NOs:2, 4, 6 or 8. The invention further provides immunogenic compositions containing BASB034 polypeptides and immunogenic fragments thereof, and a pharmaceutically acceptable carrier. Also provided are fusion proteins that contain BASB034 polypeptides and immunogenic fragments thereof.

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