Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Reexamination Certificate
2007-05-22
2007-05-22
Navarro, Mark (Department: 1645)
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
C530S300000, C530S350000, C530S327000, C424S184100, C424S185100, C424S192100
Reexamination Certificate
active
09884696
ABSTRACT:
Moraxella boviscytotoxin and a gene encodingMoraxella boviscytotoxin. Identification, isolation, cloning and identification of nucleotide sequence of theMoraxella bovisgenes mbxA, mbxB, mbxC and mbxD, partial purification of the native cytotoxin, preparation of partially purified native and a recombinantMoraxella boviscytotoxin, identification of an amino acid sequence of the cytotoxin, preparation of antibodies against theMoraxella boviscytotoxin, preparation of vaccines againstMoraxella bovis. Method for prevention and treatment of infectious bovine keratoconjunctivitis caused byMoraxella bovis.
REFERENCES:
patent: 5594107 (1997-01-01), Potter et al.
patent: 5837268 (1998-11-01), Potter et al.
patent: 6096320 (2000-08-01), Potter et al.
patent: 6180112 (2001-01-01), Highlander et al.
patent: 6475754 (2002-11-01), Bemis et al.
patent: 6797272 (2004-09-01), Potter et al.
patent: 2003/0118566 (2003-06-01), Neuman et al.
patent: 90/07525 (1990-07-01), None
patent: 01/16172 (2001-03-01), None
Ronald W. Ellis, Ph.D, Chapter 29, New Technologies for making vaccines, pp. 568-574, In Vaccines, W.B. Saunders, 1988.
Boslego, JW et al, Chapter 17, Gonorrhea vaccines, pp. 211-223, In Vaccines and Immunotherapy, Edited by Stanley J. Cryz, Jr. Pergamon Press, 1991.
Sandu, TS et al, American Journal of Veterniary Research, Jun. 1977, vol. 38(6), pp. 883-885.
Ostle, AG etal, American Journal of Veterinary Research, Sep. 1984, vol. 45(9), pp. 1848-1851.
Ostle, AG eta l, American Journal of Veterinary Research, May 1985, vol. 46(5), pp. 1011-1014.
Halenda, Ruth Marrion,Moraxella boviscytotoxin and cell detachment factor(seine protease, infectious bovine keratoconjunctivitis), vol. 59/08 of Dissertation Abstracts International, Feb. 1999, pp. 4031 -B, col. 2.
Billson et al, 1994, FEMS Microbiology Letters, vol. 124, pp. 69-73.
Billson et al, Jun. 2000, Infection and Immunity, pp. 3469-3474, vol. 68(6).
CA2014033A (sequence alignment) Oct. 7, 1990, accession No. AAQ10727 (sequence alignment abstract only).
Sequence Alignment, accession No. AAR86998, sequence in U.S. Pat. No. 5,475,098, filed Dec. 12, 1995, (sequence alignment abstract only).
Sequence alignment B30169, Highlnader, SK et al, in DNA, vol. 8, pp. 15-28, 1989, (sequence alignment abstract only).
Accession No. AAW22159, Sequence alignmnet, sequence in CA2170839A, MacInnes, J et al, (sequence alignment abstract only).
Gray et al, Vet. Microbiol., vol. 43, pp. 183-196, 1995.
Yamamoto, K et al. Infection and Immunity, Dec. 1990, vol. 58(12), pp. 4106-4116, Two step processing for activation of the cytolysin/Hemolysin ofVibrio cholerae01 Biotype E1 Tor: Nucleotide sequence of the structural gene(hlyA) and characterization of the Processed Products.
Billson, F. Mark et al, Infection and Immunity, Jun. 200, p. 3469-3474, vol. 68(6), Characterization of Hemolysin ofMoraxella bovisusing a hemolysis-neutralizing monoclonal antibody.
Gray, J. T e al, Veterinary Microbiology, vol. 43, 1995, pp. 183-196, Partial Characterization of aMoraxella boviscytolysin.
Gerbig, DG et al, Infection and Immunity, May 1992, vol. 60(5), pp. 1734-1739, May 1992, Characterization of a neutralizing monoclonal antibody toPasteurella haemolytica leukotoxin.
Lally, Edward T. et al, RTX Toxins recognize a B2 integrin on the on the surface of Human target cells, The Journal of Biological Chemistry, vol. 272(48), Nov. 28, 1997, pp. 30463-30469.
Pellett, S et al, Infection and Immunity, Aug. 1996, vol. 6, 4(8), pp. 3081-3087, Aug. 1996,Escherichia colihemolysin mutants with altered target cell specifiicity.
Smits, MA et al, Infection and Immunity, vol. 59(12), pp. 4497-4504, Dec. 1991, Cytolysins ofActinobacillus pleuropneumoniaeserotype 9.
Burrows, LL et al, Infection and Immunity, Dec. 1993, pp. 5001-5007, vol. 61(12), Molecular analysis of the leukotoxin determinants from Pasteurella haemolytica serotypes 1 to 16.
Angelos, JA et al, Veterinary Microbiology, vol. 92, pp. 363-377, 2003, An RTX operon in hemolyticMoraxella bovisis absent from nonhemolytic strains.
Hess, JF et al, Journal of Medical Microbiology, 2006, vol. 55, pp. 443-449, TheMoraxella bovisRTX toxin locus mbx defines a pathogenicity island.
Patricia S. Hoien-Dalen, et al., Comparative Characterization of the Leukocidic and Hemolytic Activity ofMoraxella bovis, Am. J. Vet. Res., 51/2:191-196 (Feb. 1990).
F. Mark Billson, et al., A Haemolytic Cell-free Preparation ofMoraxella bovisConfers Protection Against Infectious Bovine Keratoconjunctivitis,FEMS Microbiology Letters, 124:69-73 (1994).
F. Mark Billson, et al., Characterization of Hemolysin ofMoraxella bovisUsing Hemolysis-Neutralizing Monoclonal Antibody,Infection and Immunity, pp. 3469-3474 (Jun. 2000).
J. T. Gray, et al., Partial Characterizatio of aMoraxella bovisCytolysin,Veterinary Microbiology, 43:183-196, (1995).
M. K. McG. Beard, et al., Reproduction of Bovine Keratoconjunctivitis With a Purified Haemolytic and Cytotoxic Fraction ofMoraxella bovis, Veterinary Microbiology, 42:15-33 (1994).
Michael H. Brown, et al., Infectious Bovine Keratoconjunctivitis: A Review,J. Vet. Intern. Med., 12:259-266 (1998).
Angelos John A.
George Lisle W.
Hess John F.
Navarro Mark
Portner Ginny Allen
Quine Intellectual Property Law Group P.C.
The Regents of the University of California
LandOfFree
Moraxella bovis cytotoxin, cytotoxin gene, antibodies and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Moraxella bovis cytotoxin, cytotoxin gene, antibodies and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Moraxella bovis cytotoxin, cytotoxin gene, antibodies and... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3755530