Monospiroalkyl derivatives of prostaglandins

Details Monospiroalkyl derivatives of prostaglandins Monospiroalkyl derivatives of prostaglandins

1977-01-10

1978-07-04

Schwartz, Gerald A.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260617R, 260617M, 424305, 424331, 424343, 560118, C07C 4946

Patent

active

040988236

ABSTRACT:
Novel monospiroalkyl analogues or derivatives of prostaglandin A, E and F are useful modifiers of smooth muscle activity. The compounds have valuable pharmacalogical properties as platelet antiaggregating agents and gastric antisecretory agents. The compounds are also valuable pharmacological agents for increasing femoral blood flow and decreasing blood pressure and heart rate.

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