Monospecific polyclonal antibodies to shiga-like toxins

Details Monospecific polyclonal antibodies to shiga-like toxins Monospecific polyclonal antibodies to shiga-like toxins

1993-12-28

1996-04-30

Parr, Margaret

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Binds bacterium or component thereof or substance produced...

4241641, 4242341, 4242361, 4242411, 435 732, 435 737, 5303895, 5303901, A61K 39108, A61K 3940, C07K 1612, G01N 3353

Patent

active

055122825

ABSTRACT:
Disclosed herein are high titer, monospecific, polyclonal antibodies to Shiga-like toxins. Also disclosed are methods for producing such antibodies, compositions containing them, and methods for the diagnosis, prevention, and treatment of diseases caused by Shiga-like toxins. These include hemorrhagic colitis and hemolytic uremic syndrome in humans, edema disease in swine, and calf diarrhea in cattle.

REFERENCES:
patent: 3907987 (1975-09-01), Wilson
patent: 3975517 (1976-08-01), Wilson
patent: 3984539 (1976-10-01), Khouw et al.
patent: 4530833 (1985-07-01), Wilkins et al.
patent: 4533630 (1985-08-01), Wilkins et al.
patent: 4816252 (1989-03-01), Stott et al.
patent: 4863852 (1989-09-01), Wilkins et al.
patent: 4879218 (1989-11-01), Wilkins et al.
Ashkenazi et al., J. Pediatr. 113: 1008-1014, 1988.
MacLeod et al., Vet. Microbiol. 29: 309-318, 1991.
Brussow et al., 1987, Journal of Clinical Microbiology, 982-986.
Davidson et al., 1989, The Lancet, 709-712.
Archambault et al., 1988, Am. J. Vet. Res., 49(7):1084-1091.
Mietens and Keinhorst, 1979, Eur. J. Pediatr., 132:239-252.
Tacket et al., The New England Journal of Medicine, 318(19):1240-1243.
Boesman-Finkelstein, 1989, Infection and Immunity, 1227-1234.
Karmali, 1989, Clinical Microbiology Reviews, 15-38.
Samuel et al., 1990, Infection and Immunity, 58(3):611-618.
"Unravelling HUS", 1987, The Lancet, 1437-1439.
Harari et al., 1988, Infection and Immunity, 56:1618-1624.
Donohue-Rolff, 1989, Infection and Immunity, 57:3888-3893.
Boyd et al., 1991, Infection and Immunity, 59:750-757.

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