Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Animal cell – per se – expressing immunoglobulin – antibody – or...
Patent
1997-07-25
2000-03-28
Chin, Christopher L.
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
Animal cell, per se, expressing immunoglobulin, antibody, or...
435 724, 435 78, 435 792, 435 13, 435 7021, 4351722, 436518, 436524, 436528, 436529, 436530, 436531, 436534, 436548, 5303873, 5303879, 53038825, 5303893, 5303911, 5303913, 935 15, 935104, C12N 520, C07K 1636, G01N 33543, G01N 33544
Patent
active
060430877
ABSTRACT:
The invention provides a monospecific antibody that is specifically reactive with enzymatically mediated degradation products of fibrin(ogen) (i.e., fibrin, fibrinogen, and related substances). The monospecific antibody of the invention is specifically reactive with an epitope defined by an amino acid sequence SEQ ID NO:1. The invention further provides compositions containing a monospecific antibody, optionally detectably labeled, for the performance of fibrinolytic or thrombolytic analyses. The invention further provides continuous cell lines (hybridomas) that produce monospecific antibodies as described.
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Bini Alessandra
Kudryk Bohdan J.
Chin Christopher L.
Grun James L.
The New York Blood Center
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