Monosaccharide and aglycone derivatives of C-076

Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...

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26034341, 424279, 424181, 536 4, 536 9, 536 17A, A61K 3171, A61K 31365, C07H 1708

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042062055

ABSTRACT:
Derivatives of C-076 are described in which the C-076 molecule, a series of macrolides in which one of the substituents is a 4-(.alpha.-L-oleandrosyl)-.alpha.-L-oleandrose has one or both of the carbohydrate moieties removed therefrom. The compounds thus produced have profound anthelmintic, insecticidal, ectoparasiticidal and acaracidal activity and compositions for such use are also disclosed.

REFERENCES:
patent: 3923784 (1975-12-01), Kierstead et al.
patent: 3928387 (1975-12-01), Kierstead et al.
patent: 3939144 (1976-02-01), Radobolja et al.
patent: 3950360 (1976-04-01), Aoki et al.
patent: 4093629 (1978-06-01), Fisher
patent: 4134973 (1979-01-01), Fisher et al.
"Tetrahedron Letter," vol. 10, pp. 711-714, 1975.
"Jour. of Antibiotics," vol. 29, No. 6, 6/76, pp. 14-16 and pp. 35-42.

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