Monosaccharide analog-based glycosidase inhibitors

Details Monosaccharide analog-based glycosidase inhibitors Monosaccharide analog-based glycosidase inhibitors

1991-07-23

1993-07-27

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546243, 546249, 546257, 546281, 546 2, 536 187, C07D21172, C07D21158, C07D21140, C07D21102

Patent

active

052311856

ABSTRACT:
Broad spectrum glycosidase inhibitors are produced from monosaccharide lactams by conversion to amidines, amidrazones, or amidoximes. The inhibitors have the general formula: ##STR1## wherein the N and C are joined as part of a monosaccharide azaanalog ring and wherein --NRQ, together with the nitrogen and carbon atoms, form a chemical group selected from amidines, amidrazones, and amidoximes.

REFERENCES:
patent: 5081248 (1992-01-01), Zama et al.

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