Monosaccharide analog-based glycosidase inhbitors

Details Monosaccharide analog-based glycosidase inhbitors Monosaccharide analog-based glycosidase inhbitors

1995-01-19

1997-09-02

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546290, 548544, C07D21154, C07D21142, C07D207273

Patent

active

056633556

ABSTRACT:
Broad spectrum glycosidase inhibitors are produced from monosaccharide lactams by conversion to amidines, amidrazones or amidoximes. The inhibitors have the general formula: ##STR1## wherein the N and C are joined as part of a monosaccharide azaanalog ring and wherein --NRQ, together with the nitrogen and carbon atoms, form a chemical group selected from amidines, amidrazones, and amidoximes.

REFERENCES:
patent: 5081248 (1992-01-01), Zama et al.

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