Mononuclear phagocytes in therapeutic drug delivery

Details Mononuclear phagocytes in therapeutic drug delivery Mononuclear phagocytes in therapeutic drug delivery

2007-03-13

2007-03-13

Nguyen, Dave Trong (Department: 1636)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

C435S320100, C435S455000

Reexamination Certificate

active

09284009

ABSTRACT:
The invention relates to the exploitation of the migratory behavior of mononuclear phagocytes with a view to targeting therapeutic drug delivery. The invention therefore concerns the attachment or incorporation of a therapeutic agent to or into a mononuclear phagocyte and the subsequent migration of the munonuclear phagocyte to a target area.

REFERENCES:
patent: 5942434 (1999-08-01), Ratcliffe et al.
patent: 5972900 (1999-10-01), Ferkol et al.
patent: 6265390 (2001-07-01), Ratcliffe
patent: 6379647 (2002-04-01), Lewis
patent: WO 95/06120 (1995-03-01), None
patent: WO 95/21927 (1995-08-01), None
patent: WO 95/29074 (1995-11-01), None
J. Gomez-Navarro et al. Gene Therapy of Cancer Jun. 1999, Eur. J. Cancer 35 (6): 867-885.
Verma et al. Nature, vol. 389, 1997, pp. 239-242.
Orkin et al. Report and Recommendations of the Panel to Assess the NIH Investment in Research on Gene Therapy, www.nih.gov.
Kaufmann et al Xenotransplantation. 1995. Annu Rev Immunol vol 13 pp 339-367.
Crystal Transfer of genes to humans early lessons and obstacles to success, 1995. Science, vol. 270, pp. 404-410.
Nishihara et al, Endocrinology, vol. 138, No. 11 ()1997) pp 45774583.
Kluth et al, The Journal of Immunology, 2001, 166: 4728-4736 (2001).
Ferkol et al, “Receptor-Mediated Gene Transfer into Macrophages”,Proceedings of the National Academy of Sciences, U.S.A., vol. 93, Jan. 1996, pp. 101-105.
Database Medline Abstract 97077027, Erbacher et al, “Gene Transfer by DNA/Glycosylated Polylysine Complexes into Human Blood Monocyte-Derived Macrophages”,Human Gene Therapy, vol. 7, No. 6. Apr. 10, 1996, pp. 721-729.
Database Medline Abstract 95239217, Kim et al, “High Dose Methylprednisone Therapy Reduces Expression of JE/MCP-1 MRNA and Macrophage Accumulation in the Ischemic Rate Brain”.Journal of the Neurological Sciences, vol. 128, No. 1, Jan. 1995, pp. 28-35.
Knighton et al, “Oxygen tension Regulates the Expression of Angiogenes Factor by Macrophages”,Science, vol. 221, 1983, pp. 1283-1285.
Vukanovic et al, “Linomide Inhibits Angiogenesis, Growth. Matastasis, and Macrophage Infiltration within Rage Prostatic Cancers”,Cancer Research, vol. 55, 1995, pp. 1499-1504.
Leek et al, “Association of Macrophage Infiltration with Angiogenesis and Prognosis in Invasive Breast Carcinoma”.Cancer Research, vol. 56. Oct. 15, 1996. pp. 4625-4629.
Lewis et al, “Role of Macrophages in Tumour Angiogenesis: Regulation by Hypoxia”.Pathological Society of Great Britain and Ireland, 175 Meeting, vol. 182, Jul. 2-4, 1997, Sheffield, p. 1A.

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