Monomeric interferons

Details Monomeric interferons Monomeric interferons

1982-11-24

1984-02-21

Schain, Howard E.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424 85, 435 68, A61K 4502, C07G 700

Patent

active

044328958

ABSTRACT:
A method for producing monomeric interferons from oligomeric interferons, for preventing formation of oligomeric interferon from monomeric interferon, and for increasing the yield of monomeric interferon upon purification of interferon is described. The method employs a redox reagent to treat the interferon sample.

REFERENCES:
patent: 3548053 (1970-12-01), Joshi
patent: 4061538 (1977-12-01), Dorner et al.
patent: 4184917 (1980-01-01), Dorner et al.
patent: 4278661 (1981-07-01), Knight, Jr.
patent: 4289689 (1981-09-01), Friesen et al.
patent: 4289690 (1981-09-01), Pestka et al.
patent: 4382027 (1983-05-01), Braude

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